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A sensitive mass spectrometric assay for mitochondrial CoQ pool redox state in vivo

Coenzyme Q (CoQ) is an essential cofactor, primarily found in the mitochondrial inner membrane where it functions as an electron carrier in the respiratory chain, and as a lipophilic antioxidant. The redox state of the CoQ pool is the ratio of its oxidised (ubiquinone) and reduced (ubiquinol) forms,...

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Detalles Bibliográficos
Autores principales: Burger, Nils, Logan, Angela, Prime, Tracy A., Mottahedin, Amin, Caldwell, Stuart T., Krieg, Thomas, Hartley, Richard C., James, Andrew M., Murphy, Michael P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Science 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6975167/
https://www.ncbi.nlm.nih.gov/pubmed/31811922
http://dx.doi.org/10.1016/j.freeradbiomed.2019.11.028