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BMI and low vitamin D are causal factors for multiple sclerosis: A Mendelian Randomization study

OBJECTIVE: To update the causal estimates for the effects of adult body mass index (BMI), childhood BMI, and vitamin D status on multiple sclerosis (MS) risk. METHODS: We used 2-sample Mendelian randomization to determine causal estimates. Summary statistics for SNP associations with traits of inter...

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Detalles Bibliográficos
Autores principales: Jacobs, Benjamin M., Noyce, Alastair J., Giovannoni, Gavin, Dobson, Ruth
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6975169/
https://www.ncbi.nlm.nih.gov/pubmed/31937597
http://dx.doi.org/10.1212/NXI.0000000000000662