USP44 positively regulates innate immune response to DNA viruses through deubiquitinating MITA

Mediator of IRF3 activation (MITA, also known as stimulator of interferon genes, STING) senses the second messenger cyclic GMP-AMP (cGAMP) which is synthesized upon DNA virus infection and activates innate antiviral immune response. It has been demonstrated that the activity of MITA is delicately re...

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Detalles Bibliográficos
Autores principales: Zhang, Hong-Yan, Liao, Bo-Wei, Xu, Zhi-Sheng, Ran, Yong, Wang, Dong-Peng, Yang, Yan, Luo, Wei-Wei, Wang, Yan-Yi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6975528/
https://www.ncbi.nlm.nih.gov/pubmed/31968013
http://dx.doi.org/10.1371/journal.ppat.1008178

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6975528/
https://www.ncbi.nlm.nih.gov/pubmed/31968013
http://dx.doi.org/10.1371/journal.ppat.1008178

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