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Stochasticity of replication forks’ speeds plays a key role in the dynamics of DNA replication

Eukaryotic DNA replication is elaborately orchestrated to duplicate the genome timely and faithfully. Replication initiates at multiple origins from which replication forks emanate and travel bi-directionally. The complex spatio-temporal regulation of DNA replication remains incompletely understood....

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Detalles Bibliográficos
Autores principales: Yousefi, Razie, Rowicka, Maga
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6975548/
https://www.ncbi.nlm.nih.gov/pubmed/31869320
http://dx.doi.org/10.1371/journal.pcbi.1007519