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Tissue-guided LASSO for prediction of clinical drug response using preclinical samples

Prediction of clinical drug response (CDR) of cancer patients, based on their clinical and molecular profiles obtained prior to administration of the drug, can play a significant role in individualized medicine. Machine learning models have the potential to address this issue but training them requi...

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Detalles Bibliográficos
Autores principales: Huang, Edward W., Bhope, Ameya, Lim, Jing, Sinha, Saurabh, Emad, Amin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6975549/
https://www.ncbi.nlm.nih.gov/pubmed/31967990
http://dx.doi.org/10.1371/journal.pcbi.1007607