Ligand dependent gene regulation by transient ERα clustered enhancers

Unliganded Estrogen receptor alpha (ERα) has been implicated in ligand-dependent gene regulation. Upon ligand exposure, ERα binds to several EREs relatively proximal to the pre-marked, unliganded ERα-bound sites and affects transient but robust gene expression. However, the underlying mechanisms are...

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Detalles Bibliográficos
Autores principales: Saravanan, Bharath, Soota, Deepanshu, Islam, Zubairul, Majumdar, Sudeshna, Mann, Rajat, Meel, Sweety, Farooq, Umer, Walavalkar, Kaivalya, Gayen, Srimonta, Singh, Anurag Kumar, Hannenhalli, Sridhar, Notani, Dimple
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6975561/
https://www.ncbi.nlm.nih.gov/pubmed/31905229
http://dx.doi.org/10.1371/journal.pgen.1008516

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6975561/
https://www.ncbi.nlm.nih.gov/pubmed/31905229
http://dx.doi.org/10.1371/journal.pgen.1008516

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