Removal of a Conserved Disulfide Bond Does Not Compromise Mechanical Stability of a VHH Antibody Complex

[Image: see text] Single-domain VHH antibodies are promising reagents for medical therapy. A conserved disulfide bond within the VHH framework region is known to be critical for thermal stability, however, no prior studies have investigated its influence on the stability of VHH antibody–antigen comp...

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Detalles Bibliográficos
Autores principales: Liu, Haipei, Schittny, Valentin, Nash, Michael A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2019
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6975629/
https://www.ncbi.nlm.nih.gov/pubmed/31257893
http://dx.doi.org/10.1021/acs.nanolett.9b02062

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6975629/
https://www.ncbi.nlm.nih.gov/pubmed/31257893
http://dx.doi.org/10.1021/acs.nanolett.9b02062

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