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On the use of algebraic topology concepts to check the consistency of genome assembly

This paper presents a preliminary work consisting of two contributions. The first one is the design of a very efficient algorithm based on an “Overlap-Layout-Consensus” (OLC) graph to assemble the long reads provided by 3rd generation technologies. The second concerns the analysis of this graph usin...

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Detalles Bibliográficos
Autor principal: Gibrat, Jean-François
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Biophysical Society of Japan (BSJ) 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6975893/
https://www.ncbi.nlm.nih.gov/pubmed/31984196
http://dx.doi.org/10.2142/biophysico.16.0_444