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Replica exchange molecular dynamics simulation study on the mechanism of desiccation-induced structuralization of an intrinsically disordered peptide as a model of LEA proteins

Group 3 late embryogenesis abundant (G3LEA) proteins, which act as a well-characterized desiccation protectant in anhydrobiotic organisms, are structurally disordered in solution, but they acquire a predominantly α-helical structure during drying. Thus, G3LEA proteins are now accepted as intrinsical...

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Detalles Bibliográficos
Autores principales: Nishimoto, Tatsushi, Takahashi, Yuta, Miyama, Shohei, Furuta, Tadaomi, Sakurai, Minoru
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Biophysical Society of Japan (BSJ) 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6975979/
https://www.ncbi.nlm.nih.gov/pubmed/31984172
http://dx.doi.org/10.2142/biophysico.16.0_196