Active PLK1-driven metastasis is amplified by TGF-β signaling that forms a positive feedback loop in non-small cell lung cancer

Early findings that PLK1 is highly expressed in cancer have driven an exploration of its functions in metastasis. However, whether PLK1 induces metastasis in vivo and its underlying mechanisms in NSCLC have not yet been determined. Here, we show that the expression of active PLK1 phosphorylated at T...

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Detalles Bibliográficos
Autores principales: Shin, Sol-Bi, Jang, Hay-Ran, Xu, Rong, Won, Jae-Yeon, Yim, Hyungshin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6976524/
https://www.ncbi.nlm.nih.gov/pubmed/31548612
http://dx.doi.org/10.1038/s41388-019-1023-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6976524/
https://www.ncbi.nlm.nih.gov/pubmed/31548612
http://dx.doi.org/10.1038/s41388-019-1023-z

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