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Enhanced Amikacin Diffusion With Ultrasound and Microbubbles in a Mechanically Ventilated Condensed Lung Rabbit Model

The poor diffusion of intravenous antibiotics in lung tissue makes nosocomial pneumonia challenging to treat, notably in critical patients under mechanical ventilation. The combination of ultrasound and microbubbles (USMB) is an emerging method for non-invasive and targeted enhancement of uptake of...

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Detalles Bibliográficos
Autores principales: Espitalier, Fabien, Darrouzain, François, Escoffre, Jean-Michel, Ternant, David, Piver, Eric, Bouakaz, Ayache, Remerand, Francis
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6976529/
https://www.ncbi.nlm.nih.gov/pubmed/32009963
http://dx.doi.org/10.3389/fphar.2019.01562