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Enhanced Amikacin Diffusion With Ultrasound and Microbubbles in a Mechanically Ventilated Condensed Lung Rabbit Model
The poor diffusion of intravenous antibiotics in lung tissue makes nosocomial pneumonia challenging to treat, notably in critical patients under mechanical ventilation. The combination of ultrasound and microbubbles (USMB) is an emerging method for non-invasive and targeted enhancement of uptake of...
Autores principales: | Espitalier, Fabien, Darrouzain, François, Escoffre, Jean-Michel, Ternant, David, Piver, Eric, Bouakaz, Ayache, Remerand, Francis |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6976529/ https://www.ncbi.nlm.nih.gov/pubmed/32009963 http://dx.doi.org/10.3389/fphar.2019.01562 |
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