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Differential Expression of the Metabotropic P2Y Receptor Family in the Cortex Following Status Epilepticus and Neuroprotection via P2Y(1) Antagonism in Mice

Purinergic signaling via P2 receptors is now widely accepted to play a critical role during increased states of hyperexcitability and seizure-induced pathology. In the setting of seizures and epilepsy, most attention has been paid to investigating the fast-acting ATP-gated P2X receptor family. More...

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Detalles Bibliográficos
Autores principales: Alves, Mariana, Smith, Jonathon, Engel, Tobias
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6976538/
https://www.ncbi.nlm.nih.gov/pubmed/32009961
http://dx.doi.org/10.3389/fphar.2019.01558