Structural basis of subtype-selective competitive antagonism for GluN2C/2D-containing NMDA receptors

N-Methyl-D-aspartate receptors (NMDARs) play critical roles in the central nervous system. Their heterotetrameric composition generates subtypes with distinct functional properties and spatio-temporal distribution in the brain, raising the possibility for subtype-specific targeting by pharmacologica...

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Detalles Bibliográficos
Autores principales: Wang, Jue Xiang, Irvine, Mark W., Burnell, Erica S., Sapkota, Kiran, Thatcher, Robert J., Li, Minjun, Simorowski, Noriko, Volianskis, Arturas, Collingridge, Graham L., Monaghan, Daniel T., Jane, David E., Furukawa, Hiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6976569/
https://www.ncbi.nlm.nih.gov/pubmed/31969570
http://dx.doi.org/10.1038/s41467-020-14321-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6976569/
https://www.ncbi.nlm.nih.gov/pubmed/31969570
http://dx.doi.org/10.1038/s41467-020-14321-0

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