Epothilone D alters normal growth, viability and microtubule dependent intracellular functions of cortical neurons in vitro

Brain penetrant microtubule stabilising agents (MSAs) are being increasingly validated as potential therapeutic strategies for neurodegenerative diseases and traumatic injuries of the nervous system. MSAs are historically used to treat malignancies to great effect. However, this treatment strategy c...

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Detalles Bibliográficos
Autores principales: Clark, J. A., Chuckowree, J. A., Dyer, M. S., Dickson, T. C., Blizzard, C. A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6976590/
https://www.ncbi.nlm.nih.gov/pubmed/31969604
http://dx.doi.org/10.1038/s41598-020-57718-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6976590/
https://www.ncbi.nlm.nih.gov/pubmed/31969604
http://dx.doi.org/10.1038/s41598-020-57718-z

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