G Protein-Coupling of Adhesion GPCRs ADGRE2/EMR2 and ADGRE5/CD97, and Activation of G Protein Signalling by an Anti-EMR2 Antibody

The experimental evidence that Adhesion G Protein-Coupled Receptors (aGPCRs) functionally couple to heterotrimeric G proteins has been emerging in incremental steps, but attributing biological significance to their G protein signalling function still presents a major challenge. Here, utilising activ...

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Detalles Bibliográficos
Autores principales: Bhudia, Nisha, Desai, Sapna, King, Natalie, Ancellin, Nicolas, Grillot, Didier, Barnes, Ashley A., Dowell, Simon J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6976652/
https://www.ncbi.nlm.nih.gov/pubmed/31969668
http://dx.doi.org/10.1038/s41598-020-57989-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6976652/
https://www.ncbi.nlm.nih.gov/pubmed/31969668
http://dx.doi.org/10.1038/s41598-020-57989-6

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