Mechanical forces induce an asthma gene signature in healthy airway epithelial cells

Bronchospasm compresses the bronchial epithelium, and this compressive stress has been implicated in asthma pathogenesis. However, the molecular mechanisms by which this compressive stress alters pathways relevant to disease are not well understood. Using air-liquid interface cultures of primary hum...

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Detalles Bibliográficos
Autores principales: Kılıç, Ayşe, Ameli, Asher, Park, Jin-Ah, Kho, Alvin T., Tantisira, Kelan, Santolini, Marc, Cheng, Feixiong, Mitchel, Jennifer A., McGill, Maureen, O’Sullivan, Michael J., De Marzio, Margherita, Sharma, Amitabh, Randell, Scott H., Drazen, Jeffrey M., Fredberg, Jeffrey J., Weiss, Scott T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6976696/
https://www.ncbi.nlm.nih.gov/pubmed/31969610
http://dx.doi.org/10.1038/s41598-020-57755-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6976696/
https://www.ncbi.nlm.nih.gov/pubmed/31969610
http://dx.doi.org/10.1038/s41598-020-57755-8

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