TNAP inhibition attenuates cardiac fibrosis induced by myocardial infarction through deactivating TGF-β1/Smads and activating P53 signaling pathways

Tissue nonspecific alkaline phosphatase (TNAP) is expressed widely in different tissues, modulating functions of metabolism and inflammation. However, the effect of TNAP on cardiac fibrosis remains controversial and needs to be further studied. The present study aims to investigate the role of TNAP...

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Detalles Bibliográficos
Autores principales: Gao, Lei, Wang, Li-you, Liu, Zhi-qiang, Jiang, Dan, Wu, Shi-yong, Guo, Yu-qian, Tao, Hong-mei, Sun, Min, You, Lin-na, Qin, Shu, Cheng, Xiao-cheng, Xie, Jun-shi, Chang, Guang-lei, Zhang, Dong-ying
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6976710/
https://www.ncbi.nlm.nih.gov/pubmed/31969558
http://dx.doi.org/10.1038/s41419-020-2243-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6976710/
https://www.ncbi.nlm.nih.gov/pubmed/31969558
http://dx.doi.org/10.1038/s41419-020-2243-4

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