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The Upregulation of OCT4 in Acidic Extracellular pH is Associated with Gemcitabine Resistance in Cholangiocarcinoma Cell Lines

BACKGROUND: Cholangiocarcinoma (CCA), although is an uncommon liver cancer originating from bile duct epithelial cells, is one of the top 10 most fatal cancers. Chemoresistance is an unmet need always found in CCA patients. Tumor microenvironment conditions such as hypoxia, nutrient starvation and a...

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Detalles Bibliográficos
Autores principales: Choodetwattana, Phatchareeporn, Proungvitaya, Siriporn, Jearanaikoon, Patcharee, Limpaiboon, Temduang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: West Asia Organization for Cancer Prevention 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6976837/
https://www.ncbi.nlm.nih.gov/pubmed/31554372
http://dx.doi.org/10.31557/APJCP.2019.20.9.2745