Microtubule-targeting anticancer drug eribulin induces drug efflux transporter P-glycoprotein

This study examined the effects of microtubule-targeting anticancer drugs (paclitaxel, cabazitaxel, and eribulin) on the expression of drug efflux transporter P-glycoprotein, which is encoded by MDR1. Paclitaxel and eribulin induced MDR1 promoter activity in a concentration-dependent manner, while c...

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Detalles Bibliográficos
Autores principales: Nabekura, Tomohiro, Kawasaki, Tatsuya, Jimura, Misuzu, Mizuno, Koichi, Uwai, Yuichi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6976863/
https://www.ncbi.nlm.nih.gov/pubmed/31993509
http://dx.doi.org/10.1016/j.bbrep.2020.100727

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6976863/
https://www.ncbi.nlm.nih.gov/pubmed/31993509
http://dx.doi.org/10.1016/j.bbrep.2020.100727

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