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Dual inhibition of cannabinoid CB(1) receptor and inducible NOS attenuates obesity‐induced chronic kidney disease
BACKGROUND AND PURPOSE: Obesity, an important risk factor for developing chronic kidney disease (CKD), affects the kidneys by two main molecular signalling pathways: the endocannabinoid/CB(1) receptor system, whose activation in obesity promotes renal inflammation, fibrosis, and injury, and the indu...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6976880/ https://www.ncbi.nlm.nih.gov/pubmed/31454063 http://dx.doi.org/10.1111/bph.14849 |