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Glucocorticoid induces human beta cell dysfunction by involving riborepressor GAS5 LincRNA
OBJECTIVE: A widely recognized metabolic side effect of glucocorticoid (GC) therapy is steroid-induced diabetes mellitus (DM). However, studies on the molecular basis of GC-induced pancreatic beta cell dysfunction in human beta cells are lacking. The significance of non-coding RNAs in various cellul...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6976904/ https://www.ncbi.nlm.nih.gov/pubmed/32029226 http://dx.doi.org/10.1016/j.molmet.2019.12.012 |