Cargando…

Glucocorticoid induces human beta cell dysfunction by involving riborepressor GAS5 LincRNA

OBJECTIVE: A widely recognized metabolic side effect of glucocorticoid (GC) therapy is steroid-induced diabetes mellitus (DM). However, studies on the molecular basis of GC-induced pancreatic beta cell dysfunction in human beta cells are lacking. The significance of non-coding RNAs in various cellul...

Descripción completa

Detalles Bibliográficos
Autores principales: Esguerra, Jonathan L.S., Ofori, Jones K., Nagao, Mototsugu, Shuto, Yuki, Karagiannopoulos, Alexandros, Fadista, Joao, Sugihara, Hitoshi, Groop, Leif, Eliasson, Lena
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6976904/
https://www.ncbi.nlm.nih.gov/pubmed/32029226
http://dx.doi.org/10.1016/j.molmet.2019.12.012