Estrogen Induces Mammary Ductal Dysplasia via the Upregulation of Myc Expression in a DNA-Repair-Deficient Condition

Mammary ductal dysplasia is a phenotype observed in precancerous lesions and early-stage breast cancer. However, the mechanism of dysplasia formation remains elusive. Here we show, by establishing a novel dysplasia model system, that estrogen, a female hormone, has the potential to cause mammary duc...

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Detalles Bibliográficos
Autores principales: Itou, Junji, Takahashi, Rei, Sasanuma, Hiroyuki, Tsuda, Masataka, Morimoto, Suguru, Matsumoto, Yoshiaki, Ishii, Tomoko, Sato, Fumiaki, Takeda, Shunichi, Toi, Masakazu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6976935/
https://www.ncbi.nlm.nih.gov/pubmed/31978754
http://dx.doi.org/10.1016/j.isci.2020.100821

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6976935/
https://www.ncbi.nlm.nih.gov/pubmed/31978754
http://dx.doi.org/10.1016/j.isci.2020.100821

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