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Bioengineered miR-328-3p modulates GLUT1-mediated glucose uptake and metabolism to exert synergistic antiproliferative effects with chemotherapeutics

MicroRNAs (miRNAs or miRs) are small noncoding RNAs derived from genome to control target gene expression. Recently we have developed a novel platform permitting high-yield production of bioengineered miRNA agents (BERA). This study is to produce and utilize novel fully-humanized BERA/miR-328-3p mol...

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Detalles Bibliográficos
Autores principales: Yi, Wanrong, Tu, Mei-Juan, Liu, Zhenzhen, Zhang, Chao, Batra, Neelu, Yu, Ai-Xi, Yu, Ai-Ming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6976971/
https://www.ncbi.nlm.nih.gov/pubmed/31993313
http://dx.doi.org/10.1016/j.apsb.2019.11.001