Cargando…

Insulin-like growth factor 1 modulates the phosphorylation, expression, and activity of organic anion transporter 3 through protein kinase A signaling pathway

Organic anion transporter 3 (OAT3) plays a vital role in removing a broad variety of anionic drugs from kidney, thus avoiding their possible toxicity in the body. In the current study, we investigated the role of insulin-like growth factor 1 (IGF-1) in the regulation of OAT3. We showed that IGF-1 in...

Descripción completa

Detalles Bibliográficos
Autores principales: Zhang, Jinghui, Yu, Zhou, You, Guofeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6977015/
https://www.ncbi.nlm.nih.gov/pubmed/31993315
http://dx.doi.org/10.1016/j.apsb.2019.05.005