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Extreme Antibiotic Persistence via Heterogeneity-Generating Mutations Targeting Translation

Antibiotic persistence, the noninherited tolerance of a subpopulation of bacteria to high levels of antibiotics, is a bet-hedging phenomenon with broad clinical implications. Indeed, the isolation of bacteria with substantially increased persistence rates from chronic infections suggests that evolut...

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Detalles Bibliográficos
Autores principales: Khare, Anupama, Tavazoie, Saeed
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6977076/
https://www.ncbi.nlm.nih.gov/pubmed/31964772
http://dx.doi.org/10.1128/mSystems.00847-19