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Extreme Antibiotic Persistence via Heterogeneity-Generating Mutations Targeting Translation
Antibiotic persistence, the noninherited tolerance of a subpopulation of bacteria to high levels of antibiotics, is a bet-hedging phenomenon with broad clinical implications. Indeed, the isolation of bacteria with substantially increased persistence rates from chronic infections suggests that evolut...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Microbiology
2020
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6977076/ https://www.ncbi.nlm.nih.gov/pubmed/31964772 http://dx.doi.org/10.1128/mSystems.00847-19 |