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Development and Validation of a New Gas Chromatography–Tandem Mass Spectrometry Method for the Measurement of Enrichment of Glyoxylate Metabolism Analytes in Hyperoxaluria Patients Using a Stable Isotope Procedure

[Image: see text] Primary hyperoxalurias (PH) are inborn errors of glyoxylate metabolism characterized by an increase in endogenous oxalate production. Oxalate overproduction may cause calcium-oxalate crystal formation leading to kidney stones, nephrocalcinosis, and ultimately kidney failure. Twenty...

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Detalles Bibliográficos
Autores principales: van Harskamp, Dewi, Garrelfs, Sander F., Oosterveld, Michiel J. S., Groothoff, Jaap W., van Goudoever, Johannes B., Schierbeek, Henk
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2019
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6977104/
https://www.ncbi.nlm.nih.gov/pubmed/31867958
http://dx.doi.org/10.1021/acs.analchem.9b03670