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Development and Validation of a New Gas Chromatography–Tandem Mass Spectrometry Method for the Measurement of Enrichment of Glyoxylate Metabolism Analytes in Hyperoxaluria Patients Using a Stable Isotope Procedure
[Image: see text] Primary hyperoxalurias (PH) are inborn errors of glyoxylate metabolism characterized by an increase in endogenous oxalate production. Oxalate overproduction may cause calcium-oxalate crystal formation leading to kidney stones, nephrocalcinosis, and ultimately kidney failure. Twenty...
Autores principales: | van Harskamp, Dewi, Garrelfs, Sander F., Oosterveld, Michiel J. S., Groothoff, Jaap W., van Goudoever, Johannes B., Schierbeek, Henk |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American
Chemical
Society
2019
|
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6977104/ https://www.ncbi.nlm.nih.gov/pubmed/31867958 http://dx.doi.org/10.1021/acs.analchem.9b03670 |
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