Cargando…

Profound weight loss induces reactive astrogliosis in the arcuate nucleus of obese mice

OBJECTIVE: Obesity has been linked to an inflammation like state in the hypothalamus, mainly characterized by reactive gliosis (RG) of astrocytes and microglia. Here, using two diet models or pharmacological treatment, we assessed the effects of mild and drastic weight loss on RG, in the context of...

Descripción completa

Detalles Bibliográficos
Autores principales: Harrison, Luke, Pfuhlmann, Katrin, Schriever, Sonja C., Pfluger, Paul T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6977167/
https://www.ncbi.nlm.nih.gov/pubmed/30979678
http://dx.doi.org/10.1016/j.molmet.2019.03.009