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French lyophilized plasma versus normal saline for post-traumatic coagulopathy prevention and correction: PREHO-PLYO protocol for a multicenter randomized controlled clinical trial

BACKGROUND: Post-trauma bleeding induces an acute deficiency in clotting factors, which promotes bleeding and hemorrhagic shock. However, early plasma administration may reduce the severity of trauma-induced coagulopathy (TIC). Unlike fresh frozen plasma, which requires specific hospital logistics,...

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Detalles Bibliográficos
Autores principales: Jost, Daniel, Lemoine, Sabine, Lemoine, Frederic, Lanoe, Vincent, Maurin, Olga, Derkenne, Clément, Franchin Frattini, Marilyn, Delacote, Maëlle, Seguineau, Edouard, Godefroy, Anne, Hervault, Nicolas, Delhaye, Ludovic, Pouliquen, Nicolas, Louis-Delauriere, Emilie, Trichereau, Julie, Roquet, Florian, Salomé, Marina, Verret, Catherine, Bihannic, René, Jouffroy, Romain, Frattini, Benoit, Hong Tuan Ha, Vivien, Dang-Minh, Pascal, Travers, Stéphane, Bignand, Michel, Martinaud, Christophe, Garrabe, Eliane, Ausset, Sylvain, Prunet, Bertrand, Sailliol, Anne, Tourtier, Jean Pierre
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6977230/
https://www.ncbi.nlm.nih.gov/pubmed/31969168
http://dx.doi.org/10.1186/s13063-020-4049-1