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French lyophilized plasma versus normal saline for post-traumatic coagulopathy prevention and correction: PREHO-PLYO protocol for a multicenter randomized controlled clinical trial
BACKGROUND: Post-trauma bleeding induces an acute deficiency in clotting factors, which promotes bleeding and hemorrhagic shock. However, early plasma administration may reduce the severity of trauma-induced coagulopathy (TIC). Unlike fresh frozen plasma, which requires specific hospital logistics,...
Autores principales: | Jost, Daniel, Lemoine, Sabine, Lemoine, Frederic, Lanoe, Vincent, Maurin, Olga, Derkenne, Clément, Franchin Frattini, Marilyn, Delacote, Maëlle, Seguineau, Edouard, Godefroy, Anne, Hervault, Nicolas, Delhaye, Ludovic, Pouliquen, Nicolas, Louis-Delauriere, Emilie, Trichereau, Julie, Roquet, Florian, Salomé, Marina, Verret, Catherine, Bihannic, René, Jouffroy, Romain, Frattini, Benoit, Hong Tuan Ha, Vivien, Dang-Minh, Pascal, Travers, Stéphane, Bignand, Michel, Martinaud, Christophe, Garrabe, Eliane, Ausset, Sylvain, Prunet, Bertrand, Sailliol, Anne, Tourtier, Jean Pierre |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6977230/ https://www.ncbi.nlm.nih.gov/pubmed/31969168 http://dx.doi.org/10.1186/s13063-020-4049-1 |
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