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An integrated analysis of public genomic data unveils a possible functional mechanism of psoriasis risk via a long-range ERRFI1 enhancer

BACKGROUND: Psoriasis is a chronic inflammatory skin disease, for which genome-wide association studies (GWAS) have identified many genetic variants as risk markers. However, the details of underlying molecular mechanisms, especially which variants are functional, are poorly understood. METHODS: We...

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Detalles Bibliográficos
Autores principales: Kubota, Naoto, Suyama, Mikita
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6977261/
https://www.ncbi.nlm.nih.gov/pubmed/31969149
http://dx.doi.org/10.1186/s12920-020-0662-9