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13-Methylberberine improves endothelial dysfunction by inhibiting NLRP3 inflammasome activation via autophagy induction in human umbilical vein endothelial cells

BACKGROUND: Atherosclerosis, the underlying cause of the majority of cardiovascular diseases, is a lipid-driven, inflammatory disease of the large arteries. Atherosclerotic cardiovascular disease (ASCVD) threatens human lives due to high morbidity and mortality. Many studies have demonstrated that a...

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Detalles Bibliográficos
Autores principales: Peng, Zhihua, Zhan, Hong, Shao, Yijia, Xiong, Yan, Zeng, Lijin, Zhang, Cong, Liu, Zhihao, Huang, Zhenhua, Su, Huanxing, Yang, Zhen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6977264/
https://www.ncbi.nlm.nih.gov/pubmed/31993073
http://dx.doi.org/10.1186/s13020-020-0286-1