Contribution of genetic polymorphism of methylene tetrahydrofolate reductase on the effect of methotrexate in ectopic pregnancy patients

BACKGROUND: Methotrexate (MTX) is the prior drug in ectopic pregnancy (EP). However, approximately 10% of patients suffer from failure by MTX therapy. Reduced folate carrier 1 (RFC1), methylene tetrahydrofolate reductase (MTHFR), and dihydrofolate reductase (DHFR) are involved in the transport and e...

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Detalles Bibliográficos
Autores principales: Deng, Jie, Chen, Li, Xue, Heng, Zeng, Fan‐Xiang, Niu, Pei‐Guang, Shi, Dao‐Hua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6977338/
https://www.ncbi.nlm.nih.gov/pubmed/31502727
http://dx.doi.org/10.1002/jcla.23030

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6977338/
https://www.ncbi.nlm.nih.gov/pubmed/31502727
http://dx.doi.org/10.1002/jcla.23030

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