CHI3L1 promotes proliferation and improves sensitivity to cetuximab in colon cancer cells by down‐regulating p53

BACKGROUND: Chitinase 3‐like protein 1 (CHI3L1) is most likely a malignant tumor metastasis‐associated gene. However, the functions of CHI3L1 in colon cancer cell proliferation and its cetuximab sensitivity are still unclear. We aimed to investigate the mechanism of CHI3L1 in promoting colon cancer...

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Detalles Bibliográficos
Autores principales: Liu, Kaitai, Jin, Ming, Ye, Shuang, Yan, Senxiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6977395/
https://www.ncbi.nlm.nih.gov/pubmed/31536166
http://dx.doi.org/10.1002/jcla.23026

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6977395/
https://www.ncbi.nlm.nih.gov/pubmed/31536166
http://dx.doi.org/10.1002/jcla.23026

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