General Principles for the Validation of Proarrhythmia Risk Prediction Models: An Extension of the CiPA In Silico Strategy

This white paper presents principles for validating proarrhythmia risk prediction models for regulatory use as discussed at the In Silico Breakout Session of a Cardiac Safety Research Consortium/Health and Environmental Sciences Institute/US Food and Drug Administration–sponsored Think Tank Meeting...

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Detalles Bibliográficos
Autores principales: Li, Zhihua, Mirams, Gary R., Yoshinaga, Takashi, Ridder, Bradley J., Han, Xiaomei, Chen, Janell E., Stockbridge, Norman L., Wisialowski, Todd A., Damiano, Bruce, Severi, Stefano, Morissette, Pierre, Kowey, Peter R., Holbrook, Mark, Smith, Godfrey, Rasmusson, Randall L., Liu, Michael, Song, Zhen, Qu, Zhilin, Leishman, Derek J., Steidl‐Nichols, Jill, Rodriguez, Blanca, Bueno‐Orovio, Alfonso, Zhou, Xin, Passini, Elisa, Edwards, Andrew G., Morotti, Stefano, Ni, Haibo, Grandi, Eleonora, Clancy, Colleen E., Vandenberg, Jamie, Hill, Adam, Nakamura, Mikiko, Singer, Thomas, Polonchuk, Liudmila, Greiter‐Wilke, Andrea, Wang, Ken, Nave, Stephane, Fullerton, Aaron, Sobie, Eric A., Paci, Michelangelo, Musuamba Tshinanu, Flora, Strauss, David G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
White Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6977398/
https://www.ncbi.nlm.nih.gov/pubmed/31709525
http://dx.doi.org/10.1002/cpt.1647

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6977398/
https://www.ncbi.nlm.nih.gov/pubmed/31709525
http://dx.doi.org/10.1002/cpt.1647

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