Frontline Science: TNF‐α and GM‐CSF1 priming augments the role of SOS1/2 in driving activation of Ras, PI3K‐γ, and neutrophil proinflammatory responses

Circulating neutrophils are, by necessity, quiescent and relatively unresponsive to acute stimuli. In regions of inflammation, mediators can prime neutrophils to react to acute stimuli with stronger proinflammatory, pathogen‐killing responses. In neutrophils G protein‐coupled receptor (GPCR)‐driven...

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Detalles Bibliográficos
Autores principales: Suire, Sabine, Baltanas, Fernando C., Segonds‐Pichon, Anne, Davidson, Keith, Santos, Eugenio, Hawkins, Phillip T., Stephens, Len R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Spotlight on Leading Edge Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6977543/
https://www.ncbi.nlm.nih.gov/pubmed/30720883
http://dx.doi.org/10.1002/JLB.2HI0918-359RR

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6977543/
https://www.ncbi.nlm.nih.gov/pubmed/30720883
http://dx.doi.org/10.1002/JLB.2HI0918-359RR

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