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Chemoselective formal β-functionalization of substituted aliphatic amides enabled by a facile stereoselective oxidation event
Aliphatic C–H functionalization is a topic of current intense interest in organic synthesis. Herein, we report that a facile and stereoselective dehydrogenation event enables the functionalization of aliphatic amides at different positions in a one-pot fashion. Derivatives of relevant pharmaceutical...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Royal Society of Chemistry
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6977552/ https://www.ncbi.nlm.nih.gov/pubmed/32015806 http://dx.doi.org/10.1039/c9sc03715b |