Attenuation of diabetic kidney injury in DPP4-deficient rats; role of GLP-1 on the suppression of AGE formation by inducing glyoxalase 1

Dipeptidyl peptidase 4 (DPP4) inactivates incretin hormone glucagon-like peptide-1. DPP4 inhibitors may exert beneficial effects on diabetic nephropathy (DN) independently of glycemic control; however, the mechanisms underlying are not fully understood. Here, we investigated the mechanisms of the be...

Descripción completa

Detalles Bibliográficos
Autores principales: Sarker, Mithun Kumer, Lee, Jong Han, Lee, Dae Ho, Chun, Kwang-Hoon, Jun, Hee-Sook
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals 2020
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6977656/
https://www.ncbi.nlm.nih.gov/pubmed/31905169
http://dx.doi.org/10.18632/aging.102643

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6977656/
https://www.ncbi.nlm.nih.gov/pubmed/31905169
http://dx.doi.org/10.18632/aging.102643

Ejemplares similares