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STARD1 and NPC1 expression as pathological markers associated with astrogliosis in post-mortem brains from patients with Alzheimer's disease and Down syndrome

Alzheimer´s disease (AD) is a progressive neurodegenerative disorder of complex etiology, while Down syndrome (DS) is considered a genetically determined form of AD. Alterations in cholesterol homeostasis have been linked to AD although the role in this association is not well understood. Increased...

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Detalles Bibliográficos
Autores principales: Arenas, Fabian, Castro, Fernanda, Nuñez, Susana, Gay, Gemma, Garcia-Ruiz, Carmen, Fernandez-Checa, Jose C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6977657/
https://www.ncbi.nlm.nih.gov/pubmed/31902793
http://dx.doi.org/10.18632/aging.102641