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STARD1 and NPC1 expression as pathological markers associated with astrogliosis in post-mortem brains from patients with Alzheimer's disease and Down syndrome
Alzheimer´s disease (AD) is a progressive neurodegenerative disorder of complex etiology, while Down syndrome (DS) is considered a genetically determined form of AD. Alterations in cholesterol homeostasis have been linked to AD although the role in this association is not well understood. Increased...
Autores principales: | Arenas, Fabian, Castro, Fernanda, Nuñez, Susana, Gay, Gemma, Garcia-Ruiz, Carmen, Fernandez-Checa, Jose C. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6977657/ https://www.ncbi.nlm.nih.gov/pubmed/31902793 http://dx.doi.org/10.18632/aging.102641 |
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