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Resveratrol targets PD-L1 glycosylation and dimerization to enhance antitumor T-cell immunity

New strategies to block the immune evasion activity of programmed death ligand-1 (PD-L1) are urgently needed. When exploring the PD-L1-targeted effects of mechanistically diverse metabolism-targeting drugs, exposure to the dietary polyphenol resveratrol (RSV) revealed its differential capacity to ge...

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Detalles Bibliográficos
Autores principales: Verdura, Sara, Cuyàs, Elisabet, Cortada, Eric, Brunet, Joan, Lopez-Bonet, Eugeni, Martin-Castillo, Begoña, Bosch-Barrera, Joaquim, Encinar, José Antonio, Menendez, Javier A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6977679/
https://www.ncbi.nlm.nih.gov/pubmed/31901900
http://dx.doi.org/10.18632/aging.102646