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Spermidine alleviates cardiac aging by improving mitochondrial biogenesis and function

Polyamines have been shown to delay cellular and organismal aging and to provide cardiovascular protection in humans. Because age-related cardiovascular dysfunction is often accompanied by impaired mitochondrial biogenesis and function, we explored the ability of spermidine (SPD), a major mammalian...

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Detalles Bibliográficos
Autores principales: Wang, Junying, Li, Shaoqi, Wang, Ju, Wu, Feixiang, Chen, Yuhan, Zhang, Hao, Guo, Yubo, Lin, Yan, Li, Lingxu, Yu, Xue, Liu, Ting, Zhao, Yajun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6977682/
https://www.ncbi.nlm.nih.gov/pubmed/31907336
http://dx.doi.org/10.18632/aging.102647