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Long non-coding RNA RNF7 promotes the cardiac fibrosis in rat model via miR-543/THBS1 axis and TGFβ1 activation

Cardiac fibrosis (CF) is regulated by multiple factors, including transforming growth factor β1 (TGFβ1) and non-coding RNAs. Thrombospondin 1 (TSP1) is a physiologic regulator of TGFβ activation. Here, we performed microarray analyses on mRNAs and lncRNAs differentially-expressed in the CF and norma...

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Detalles Bibliográficos
Autores principales: Ouyang, Fan, Liu, Xiangyang, Liu, Guoan, Qiu, Haihua, He, Yi, Hu, Hongyu, Jiang, Ping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6977683/
https://www.ncbi.nlm.nih.gov/pubmed/31913855
http://dx.doi.org/10.18632/aging.102463