Ubenimex induces autophagy inhibition and EMT suppression to overcome cisplatin resistance in GC cells by perturbing the CD13/EMP3/PI3K/AKT/NF-κB axis

Cisplatin (CDDP)-based chemotherapy is a standard treatment for gastric cancer (GC). However, chemoresistance is a major obstacle for CDDP application. Exploring underlying mechanisms of CDDP resistance development in GC and selecting an effective strategy to overcome CDDP resistance remain a challe...

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Detalles Bibliográficos
Autores principales: Guo, Qie, Jing, Fan-Jing, Xu, Wen, Li, Xiao, Li, Xin, Sun, Jia-Lin, Xing, Xiao-Min, Zhou, Chang-Kai, Jing, Fan-Bo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals 2019
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6977684/
https://www.ncbi.nlm.nih.gov/pubmed/31895687
http://dx.doi.org/10.18632/aging.102598

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6977684/
https://www.ncbi.nlm.nih.gov/pubmed/31895687
http://dx.doi.org/10.18632/aging.102598

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