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Epithelial cell senescence induces pulmonary fibrosis through Nanog-mediated fibroblast activation

Idiopathic pulmonary fibrosis (IPF) is a chronic and progressive lung disease tightly correlated with aging. The pathological features of IPF include epithelial cell senescence and abundant foci of highly activated pulmonary fibroblasts. However, the underlying mechanism between epithelial cell sene...

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Detalles Bibliográficos
Autores principales: Chen, Xiang, Xu, Hongyang, Hou, Jiwei, Wang, Hui, Zheng, Yi, Li, Hui, Cai, Hourong, Han, Xiaodong, Dai, Jinghong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6977687/
https://www.ncbi.nlm.nih.gov/pubmed/31891567
http://dx.doi.org/10.18632/aging.102613