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Epithelial cell senescence induces pulmonary fibrosis through Nanog-mediated fibroblast activation
Idiopathic pulmonary fibrosis (IPF) is a chronic and progressive lung disease tightly correlated with aging. The pathological features of IPF include epithelial cell senescence and abundant foci of highly activated pulmonary fibroblasts. However, the underlying mechanism between epithelial cell sene...
Autores principales: | Chen, Xiang, Xu, Hongyang, Hou, Jiwei, Wang, Hui, Zheng, Yi, Li, Hui, Cai, Hourong, Han, Xiaodong, Dai, Jinghong |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6977687/ https://www.ncbi.nlm.nih.gov/pubmed/31891567 http://dx.doi.org/10.18632/aging.102613 |
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