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Concomitant memantine and Lactobacillus plantarum treatment attenuates cognitive impairments in APP/PS1 mice

Trimethylamine-N-oxide (TMAO) is a gut microbial metabolite that promotes Alzheimer’s disease (AD) progression. Given that probiotics can alleviate AD symptoms by inhibiting the synthesis of TMAO, here we investigated the correlation between TMAO and cognitive deterioration by measuring TMAO levels...

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Detalles Bibliográficos
Autores principales: Wang, Qiu-Jun, Shen, Yue-E, Wang, Xin, Fu, Shuang, Zhang, Xin, Zhang, Yi-Na, Wang, Rui-Tao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6977692/
https://www.ncbi.nlm.nih.gov/pubmed/31907339
http://dx.doi.org/10.18632/aging.102645