Up-regulation of microRNA-375 ameliorates the damage of dopaminergic neurons, reduces oxidative stress and inflammation in Parkinson’s disease by inhibiting SP1

Background: This study is conducted to investigate the protective role of elevated microRNA-375 (miR-375) in dopaminergic neurons in Parkinson’s disease through down-regulating transcription factor specificity protein 1 (SP1). Results: The successfully modeled rats with Parkinson’s disease showed ag...

Descripción completa

Detalles Bibliográficos
Autores principales: Cai, Li-Jun, Tu, Li, Li, Tian, Yang, Xiu-Lin, Ren, Yi-Pin, Gu, Ran, Zhang, Qian, Yao, Huan, Qu, Xiang, Wang, Qian, Tian, Jin-Yong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals 2020
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6977707/
https://www.ncbi.nlm.nih.gov/pubmed/31927536
http://dx.doi.org/10.18632/aging.102649

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6977707/
https://www.ncbi.nlm.nih.gov/pubmed/31927536
http://dx.doi.org/10.18632/aging.102649

Ejemplares similares